diff --git a/editor/editor_node.cpp b/editor/editor_node.cpp
index 8a443b958b2..c007a27068b 100644
--- a/editor/editor_node.cpp
+++ b/editor/editor_node.cpp
@@ -2490,7 +2490,7 @@ void EditorNode::_menu_option_confirm(int p_option, bool p_confirmed) {
 			export_template_manager->popup_manager();
 
 		} break;
-		case SETTINGS_TOGGLE_FULLSCREN: {
+		case SETTINGS_TOGGLE_FULLSCREEN: {
 
 			OS::get_singleton()->set_window_fullscreen(!OS::get_singleton()->is_window_fullscreen());
 
@@ -5058,7 +5058,11 @@ EditorNode::EditorNode() {
 	srt->add_child(tabbar_container);
 	tabbar_container->add_child(scene_tabs);
 	distraction_free = memnew(ToolButton);
+#ifdef OSX_ENABLED
+	distraction_free->set_shortcut(ED_SHORTCUT("editor/distraction_free_mode", TTR("Distraction Free Mode"), KEY_MASK_CMD | KEY_MASK_CTRL | KEY_D));
+#else
 	distraction_free->set_shortcut(ED_SHORTCUT("editor/distraction_free_mode", TTR("Distraction Free Mode"), KEY_MASK_CMD | KEY_MASK_SHIFT | KEY_F11));
+#endif
 	distraction_free->set_tooltip(TTR("Toggle distraction-free mode."));
 	distraction_free->connect("pressed", this, "_toggle_distraction_free_mode");
 	distraction_free->set_icon(gui_base->get_icon("DistractionFree", "EditorIcons"));
@@ -5167,7 +5171,7 @@ EditorNode::EditorNode() {
 	p->add_shortcut(ED_SHORTCUT("editor/save_scene_as", TTR("Save Scene As..."), KEY_MASK_SHIFT + KEY_MASK_CMD + KEY_S), FILE_SAVE_AS_SCENE);
 	p->add_shortcut(ED_SHORTCUT("editor/save_all_scenes", TTR("Save all Scenes"), KEY_MASK_ALT + KEY_MASK_SHIFT + KEY_MASK_CMD + KEY_S), FILE_SAVE_ALL_SCENES);
 	p->add_separator();
-	p->add_shortcut(ED_SHORTCUT("editor/close_scene", TTR("Close Scene"), KEY_MASK_SHIFT + KEY_MASK_CTRL + KEY_W), FILE_CLOSE);
+	p->add_shortcut(ED_SHORTCUT("editor/close_scene", TTR("Close Scene"), KEY_MASK_SHIFT + KEY_MASK_CMD + KEY_W), FILE_CLOSE);
 	p->add_separator();
 	p->add_submenu_item(TTR("Open Recent"), "RecentScenes", FILE_OPEN_RECENT);
 	p->add_separator();
@@ -5221,7 +5225,7 @@ EditorNode::EditorNode() {
 #ifdef OSX_ENABLED
 	p->add_item(TTR("Quit to Project List"), RUN_PROJECT_MANAGER, KEY_MASK_SHIFT + KEY_MASK_ALT + KEY_Q);
 #else
-	p->add_item(TTR("Quit to Project List"), RUN_PROJECT_MANAGER, KEY_MASK_SHIFT + KEY_MASK_CTRL + KEY_Q);
+	p->add_item(TTR("Quit to Project List"), RUN_PROJECT_MANAGER, KEY_MASK_SHIFT + KEY_MASK_CMD + KEY_Q);
 #endif
 
 	PanelContainer *editor_region = memnew(PanelContainer);
@@ -5270,7 +5274,11 @@ EditorNode::EditorNode() {
 	p->add_child(editor_layouts);
 	editor_layouts->connect("id_pressed", this, "_layout_menu_option");
 	p->add_submenu_item(TTR("Editor Layout"), "Layouts");
-	p->add_shortcut(ED_SHORTCUT("editor/fullscreen_mode", TTR("Toggle Fullscreen"), KEY_MASK_SHIFT | KEY_F11), SETTINGS_TOGGLE_FULLSCREN);
+#ifdef OSX_ENABLED
+	p->add_shortcut(ED_SHORTCUT("editor/fullscreen_mode", TTR("Toggle Fullscreen"), KEY_MASK_CMD | KEY_MASK_CTRL | KEY_F), SETTINGS_TOGGLE_FULLSCREEN);
+#else
+	p->add_shortcut(ED_SHORTCUT("editor/fullscreen_mode", TTR("Toggle Fullscreen"), KEY_MASK_SHIFT | KEY_F11), SETTINGS_TOGGLE_FULLSCREEN);
+#endif
 	p->add_separator();
 	p->add_item(TTR("Manage Export Templates"), SETTINGS_MANAGE_EXPORT_TEMPLATES);
 
@@ -5311,7 +5319,11 @@ EditorNode::EditorNode() {
 	play_button->set_focus_mode(Control::FOCUS_NONE);
 	play_button->connect("pressed", this, "_menu_option", make_binds(RUN_PLAY));
 	play_button->set_tooltip(TTR("Play the project."));
+#ifdef OSX_ENABLED
+	play_button->set_shortcut(ED_SHORTCUT("editor/play", TTR("Play"), KEY_MASK_CMD | KEY_B));
+#else
 	play_button->set_shortcut(ED_SHORTCUT("editor/play", TTR("Play"), KEY_F5));
+#endif
 
 	pause_button = memnew(ToolButton);
 	pause_button->set_toggle_mode(true);
@@ -5320,7 +5332,11 @@ EditorNode::EditorNode() {
 	pause_button->set_tooltip(TTR("Pause the scene"));
 	pause_button->set_disabled(true);
 	play_hb->add_child(pause_button);
+#ifdef OSX_ENABLED
+	pause_button->set_shortcut(ED_SHORTCUT("editor/pause_scene", TTR("Pause Scene"), KEY_MASK_CMD | KEY_MASK_CTRL | KEY_Y));
+#else
 	pause_button->set_shortcut(ED_SHORTCUT("editor/pause_scene", TTR("Pause Scene"), KEY_F7));
+#endif
 
 	stop_button = memnew(ToolButton);
 	play_hb->add_child(stop_button);
@@ -5329,7 +5345,11 @@ EditorNode::EditorNode() {
 	stop_button->connect("pressed", this, "_menu_option", make_binds(RUN_STOP));
 	stop_button->set_tooltip(TTR("Stop the scene."));
 	stop_button->set_disabled(true);
+#ifdef OSX_ENABLED
+	stop_button->set_shortcut(ED_SHORTCUT("editor/stop", TTR("Stop"), KEY_MASK_CMD | KEY_PERIOD));
+#else
 	stop_button->set_shortcut(ED_SHORTCUT("editor/stop", TTR("Stop"), KEY_F8));
+#endif
 
 	run_native = memnew(EditorRunNative);
 	play_hb->add_child(run_native);
@@ -5347,7 +5367,11 @@ EditorNode::EditorNode() {
 	play_scene_button->set_icon(gui_base->get_icon("PlayScene", "EditorIcons"));
 	play_scene_button->connect("pressed", this, "_menu_option", make_binds(RUN_PLAY_SCENE));
 	play_scene_button->set_tooltip(TTR("Play the edited scene."));
+#ifdef OSX_ENABLED
+	play_scene_button->set_shortcut(ED_SHORTCUT("editor/play_scene", TTR("Play Scene"), KEY_MASK_CMD | KEY_R));
+#else
 	play_scene_button->set_shortcut(ED_SHORTCUT("editor/play_scene", TTR("Play Scene"), KEY_F6));
+#endif
 
 	play_custom_scene_button = memnew(ToolButton);
 	play_hb->add_child(play_custom_scene_button);
@@ -5356,7 +5380,11 @@ EditorNode::EditorNode() {
 	play_custom_scene_button->set_icon(gui_base->get_icon("PlayCustom", "EditorIcons"));
 	play_custom_scene_button->connect("pressed", this, "_menu_option", make_binds(RUN_PLAY_CUSTOM_SCENE));
 	play_custom_scene_button->set_tooltip(TTR("Play custom scene"));
+#ifdef OSX_ENABLED
+	play_custom_scene_button->set_shortcut(ED_SHORTCUT("editor/play_custom_scene", TTR("Play Custom Scene"), KEY_MASK_CMD | KEY_MASK_SHIFT | KEY_R));
+#else
 	play_custom_scene_button->set_shortcut(ED_SHORTCUT("editor/play_custom_scene", TTR("Play Custom Scene"), KEY_MASK_CMD | KEY_MASK_SHIFT | KEY_F5));
+#endif
 
 	progress_hb = memnew(BackgroundProgress);
 
@@ -5868,10 +5896,17 @@ EditorNode::EditorNode() {
 	print_handler.userdata = this;
 	add_print_handler(&print_handler);
 
+#ifdef OSX_ENABLED
+	ED_SHORTCUT("editor/editor_2d", TTR("Open 2D Editor"), KEY_MASK_ALT | KEY_1);
+	ED_SHORTCUT("editor/editor_3d", TTR("Open 3D Editor"), KEY_MASK_ALT | KEY_2);
+	ED_SHORTCUT("editor/editor_script", TTR("Open Script Editor"), KEY_MASK_ALT | KEY_3);
+	ED_SHORTCUT("editor/editor_help", TTR("Search Help"), KEY_MASK_ALT | KEY_SPACE);
+#else
 	ED_SHORTCUT("editor/editor_2d", TTR("Open 2D Editor"), KEY_F1);
 	ED_SHORTCUT("editor/editor_3d", TTR("Open 3D Editor"), KEY_F2);
 	ED_SHORTCUT("editor/editor_script", TTR("Open Script Editor"), KEY_F3); //hack neded for script editor F3 search to work :) Assign like this or don't use F3
 	ED_SHORTCUT("editor/editor_help", TTR("Search Help"), KEY_F4);
+#endif
 	ED_SHORTCUT("editor/editor_assetlib", TTR("Open Asset Library"));
 	ED_SHORTCUT("editor/editor_next", TTR("Open the next Editor"));
 	ED_SHORTCUT("editor/editor_prev", TTR("Open the previous Editor"));
diff --git a/editor/editor_node.h b/editor/editor_node.h
index 6395293c576..795b202e876 100644
--- a/editor/editor_node.h
+++ b/editor/editor_node.h
@@ -180,7 +180,7 @@ private:
 		SETTINGS_LAYOUT_DEFAULT,
 		SETTINGS_MANAGE_EXPORT_TEMPLATES,
 		SETTINGS_PICK_MAIN_SCENE,
-		SETTINGS_TOGGLE_FULLSCREN,
+		SETTINGS_TOGGLE_FULLSCREEN,
 		SETTINGS_HELP,
 		SCENE_TAB_CLOSE,
 
diff --git a/editor/editor_settings.cpp b/editor/editor_settings.cpp
index 6d64cc3f0ea..136bdaeb5b2 100644
--- a/editor/editor_settings.cpp
+++ b/editor/editor_settings.cpp
@@ -1351,33 +1351,9 @@ struct ShortCutMapping {
 Ref<ShortCut> ED_SHORTCUT(const String &p_path, const String &p_name, uint32_t p_keycode) {
 
 #ifdef OSX_ENABLED
-	static const ShortCutMapping macos_mappings[] = {
-		{ "editor/play", KEY_MASK_CMD | KEY_B },
-		{ "editor/play_scene", KEY_MASK_CMD | KEY_R },
-		{ "editor/pause_scene", KEY_MASK_CMD | KEY_MASK_CTRL | KEY_Y },
-		{ "editor/stop", KEY_MASK_CMD | KEY_PERIOD },
-		{ "editor/play_custom_scene", KEY_MASK_SHIFT | KEY_MASK_CMD | KEY_R },
-		{ "editor/editor_2d", KEY_MASK_ALT | KEY_1 },
-		{ "editor/editor_3d", KEY_MASK_ALT | KEY_2 },
-		{ "editor/editor_script", KEY_MASK_ALT | KEY_3 },
-		{ "editor/editor_help", KEY_MASK_ALT | KEY_SPACE },
-		{ "editor/fullscreen_mode", KEY_MASK_CMD | KEY_MASK_CTRL | KEY_F },
-		{ "editor/distraction_free_mode", KEY_MASK_CMD | KEY_MASK_CTRL | KEY_D },
-		{ "script_text_editor/contextual_help", KEY_MASK_ALT | KEY_MASK_SHIFT | KEY_SPACE },
-		{ "script_text_editor/find_next", KEY_MASK_CMD | KEY_G },
-		{ "script_text_editor/find_previous", KEY_MASK_CMD | KEY_MASK_SHIFT | KEY_G },
-		{ "script_text_editor/toggle_breakpoint", KEY_MASK_CMD | KEY_MASK_SHIFT | KEY_B }
-	};
-
+	// Use Cmd+Backspace as a general replacement for Delete shortcuts on macOS
 	if (p_keycode == KEY_DELETE) {
 		p_keycode = KEY_MASK_CMD | KEY_BACKSPACE;
-	} else {
-		for (int i = 0; i < sizeof(macos_mappings) / sizeof(ShortCutMapping); i++) {
-			if (p_path == macos_mappings[i].path) {
-				p_keycode = macos_mappings[i].keycode;
-				break;
-			}
-		}
 	}
 #endif
 
diff --git a/editor/plugins/script_text_editor.cpp b/editor/plugins/script_text_editor.cpp
index 7462970d8af..466b45a5fd9 100644
--- a/editor/plugins/script_text_editor.cpp
+++ b/editor/plugins/script_text_editor.cpp
@@ -1664,7 +1664,7 @@ void ScriptTextEditor::register_editor() {
 	ED_SHORTCUT("script_text_editor/select_all", TTR("Select All"), KEY_MASK_CMD | KEY_A);
 	ED_SHORTCUT("script_text_editor/move_up", TTR("Move Up"), KEY_MASK_ALT | KEY_UP);
 	ED_SHORTCUT("script_text_editor/move_down", TTR("Move Down"), KEY_MASK_ALT | KEY_DOWN);
-	ED_SHORTCUT("script_text_editor/delete_line", TTR("Delete Line"), KEY_MASK_CTRL | KEY_MASK_SHIFT | KEY_K);
+	ED_SHORTCUT("script_text_editor/delete_line", TTR("Delete Line"), KEY_MASK_CMD | KEY_MASK_SHIFT | KEY_K);
 
 	//leave these at zero, same can be accomplished with tab/shift-tab, including selection
 	//the next/previous in history shortcut in this case makes a lot more sene.
@@ -1677,34 +1677,46 @@ void ScriptTextEditor::register_editor() {
 	ED_SHORTCUT("script_text_editor/unfold_all_lines", TTR("Unfold All Lines"), 0);
 #ifdef OSX_ENABLED
 	ED_SHORTCUT("script_text_editor/clone_down", TTR("Clone Down"), KEY_MASK_SHIFT | KEY_MASK_CMD | KEY_C);
-	ED_SHORTCUT("script_text_editor/complete_symbol", TTR("Complete Symbol"), KEY_MASK_CTRL | KEY_SPACE);
 #else
 	ED_SHORTCUT("script_text_editor/clone_down", TTR("Clone Down"), KEY_MASK_CMD | KEY_B);
-	ED_SHORTCUT("script_text_editor/complete_symbol", TTR("Complete Symbol"), KEY_MASK_CMD | KEY_SPACE);
 #endif
-	ED_SHORTCUT("script_text_editor/trim_trailing_whitespace", TTR("Trim Trailing Whitespace"), KEY_MASK_CTRL | KEY_MASK_ALT | KEY_T);
-	ED_SHORTCUT("script_text_editor/convert_indent_to_spaces", TTR("Convert Indent To Spaces"), KEY_MASK_CTRL | KEY_MASK_SHIFT | KEY_Y);
-	ED_SHORTCUT("script_text_editor/convert_indent_to_tabs", TTR("Convert Indent To Tabs"), KEY_MASK_CTRL | KEY_MASK_SHIFT | KEY_X);
+	ED_SHORTCUT("script_text_editor/complete_symbol", TTR("Complete Symbol"), KEY_MASK_CMD | KEY_SPACE);
+	ED_SHORTCUT("script_text_editor/trim_trailing_whitespace", TTR("Trim Trailing Whitespace"), KEY_MASK_CMD | KEY_MASK_ALT | KEY_T);
+	ED_SHORTCUT("script_text_editor/convert_indent_to_spaces", TTR("Convert Indent To Spaces"), KEY_MASK_CMD | KEY_MASK_SHIFT | KEY_Y);
+	ED_SHORTCUT("script_text_editor/convert_indent_to_tabs", TTR("Convert Indent To Tabs"), KEY_MASK_CMD | KEY_MASK_SHIFT | KEY_X);
 	ED_SHORTCUT("script_text_editor/auto_indent", TTR("Auto Indent"), KEY_MASK_CMD | KEY_I);
 
+#ifdef OSX_ENABLED
+	ED_SHORTCUT("script_text_editor/toggle_breakpoint", TTR("Toggle Breakpoint"), KEY_MASK_CMD | KEY_MASK_SHIFT | KEY_B);
+#else
 	ED_SHORTCUT("script_text_editor/toggle_breakpoint", TTR("Toggle Breakpoint"), KEY_F9);
-	ED_SHORTCUT("script_text_editor/remove_all_breakpoints", TTR("Remove All Breakpoints"), KEY_MASK_CTRL | KEY_MASK_SHIFT | KEY_F9);
-	ED_SHORTCUT("script_text_editor/goto_next_breakpoint", TTR("Goto Next Breakpoint"), KEY_MASK_CTRL | KEY_PERIOD);
-	ED_SHORTCUT("script_text_editor/goto_previous_breakpoint", TTR("Goto Previous Breakpoint"), KEY_MASK_CTRL | KEY_COMMA);
+#endif
+	ED_SHORTCUT("script_text_editor/remove_all_breakpoints", TTR("Remove All Breakpoints"), KEY_MASK_CMD | KEY_MASK_SHIFT | KEY_F9);
+	ED_SHORTCUT("script_text_editor/goto_next_breakpoint", TTR("Goto Next Breakpoint"), KEY_MASK_CMD | KEY_PERIOD);
+	ED_SHORTCUT("script_text_editor/goto_previous_breakpoint", TTR("Goto Previous Breakpoint"), KEY_MASK_CMD | KEY_COMMA);
 
 	ED_SHORTCUT("script_text_editor/convert_to_uppercase", TTR("Convert To Uppercase"), KEY_MASK_SHIFT | KEY_F4);
 	ED_SHORTCUT("script_text_editor/convert_to_lowercase", TTR("Convert To Lowercase"), KEY_MASK_SHIFT | KEY_F3);
 	ED_SHORTCUT("script_text_editor/capitalize", TTR("Capitalize"), KEY_MASK_SHIFT | KEY_F2);
 
 	ED_SHORTCUT("script_text_editor/find", TTR("Find..."), KEY_MASK_CMD | KEY_F);
+#ifdef OSX_ENABLED
+	ED_SHORTCUT("script_text_editor/find_next", TTR("Find Next"), KEY_MASK_CMD | KEY_G);
+	ED_SHORTCUT("script_text_editor/find_previous", TTR("Find Previous"), KEY_MASK_CMD | KEY_MASK_SHIFT | KEY_G);
+#else
 	ED_SHORTCUT("script_text_editor/find_next", TTR("Find Next"), KEY_F3);
 	ED_SHORTCUT("script_text_editor/find_previous", TTR("Find Previous"), KEY_MASK_SHIFT | KEY_F3);
+#endif
 	ED_SHORTCUT("script_text_editor/replace", TTR("Replace..."), KEY_MASK_CMD | KEY_R);
 
 	ED_SHORTCUT("script_text_editor/goto_function", TTR("Goto Function..."), KEY_MASK_SHIFT | KEY_MASK_CMD | KEY_F);
 	ED_SHORTCUT("script_text_editor/goto_line", TTR("Goto Line..."), KEY_MASK_CMD | KEY_L);
 
+#ifdef OSX_ENABLED
+	ED_SHORTCUT("script_text_editor/contextual_help", TTR("Contextual Help"), KEY_MASK_ALT | KEY_MASK_SHIFT | KEY_SPACE);
+#else
 	ED_SHORTCUT("script_text_editor/contextual_help", TTR("Contextual Help"), KEY_MASK_SHIFT | KEY_F1);
+#endif
 
 	ScriptEditor::register_create_script_editor_function(create_editor);
 }