diff --git a/modules/openxr/SCsub b/modules/openxr/SCsub
index d5abbe4c725..fbff4c7f8fa 100644
--- a/modules/openxr/SCsub
+++ b/modules/openxr/SCsub
@@ -28,6 +28,11 @@ elif env["platform"] == "linuxbsd":
     env_openxr.AppendUnique(CPPDEFINES=["HAVE_SECURE_GETENV"])
 elif env["platform"] == "windows":
     env_openxr.AppendUnique(CPPDEFINES=["XR_OS_WINDOWS", "NOMINMAX", "XR_USE_PLATFORM_WIN32"])
+elif env["platform"] == "macos":
+    env_openxr.AppendUnique(CPPDEFINES=["XR_OS_APPLE"])
+
+    # There does not seem to be a XR_USE_PLATFORM_XYZ for Apple
+
 
 # may need to check and set:
 # - XR_USE_TIMESPEC
@@ -95,7 +100,7 @@ if env["platform"] == "android":
     env_openxr.add_source_files(module_obj, "extensions/openxr_android_extension.cpp")
 if env["vulkan"]:
     env_openxr.add_source_files(module_obj, "extensions/openxr_vulkan_extension.cpp")
-if env["opengl3"]:
+if env["opengl3"] and env["platform"] != "macos":
     env_openxr.add_source_files(module_obj, "extensions/openxr_opengl_extension.cpp")
 
 env_openxr.add_source_files(module_obj, "extensions/openxr_palm_pose_extension.cpp")
diff --git a/modules/openxr/config.py b/modules/openxr/config.py
index e503f127391..8ed06a1606d 100644
--- a/modules/openxr/config.py
+++ b/modules/openxr/config.py
@@ -1,5 +1,5 @@
 def can_build(env, platform):
-    if platform in ("linuxbsd", "windows", "android"):
+    if platform in ("linuxbsd", "windows", "android", "macos"):
         return env["openxr"] and not env["disable_3d"]
     else:
         # not supported on these platforms
diff --git a/modules/openxr/openxr_api.cpp b/modules/openxr/openxr_api.cpp
index 4ab280f3c37..c5efe609c2a 100644
--- a/modules/openxr/openxr_api.cpp
+++ b/modules/openxr/openxr_api.cpp
@@ -47,7 +47,7 @@
 #ifdef VULKAN_ENABLED
 #define XR_USE_GRAPHICS_API_VULKAN
 #endif
-#ifdef GLES3_ENABLED
+#if defined(GLES3_ENABLED) && !defined(MACOS_ENABLED)
 #ifdef ANDROID_ENABLED
 #define XR_USE_GRAPHICS_API_OPENGL_ES
 #include <EGL/egl.h>
@@ -72,7 +72,7 @@
 #include "extensions/openxr_vulkan_extension.h"
 #endif
 
-#ifdef GLES3_ENABLED
+#if defined(GLES3_ENABLED) && !defined(MACOS_ENABLED)
 #include "extensions/openxr_opengl_extension.h"
 #endif
 
@@ -1306,7 +1306,7 @@ bool OpenXRAPI::initialize(const String &p_rendering_driver) {
 		ERR_FAIL_V(false);
 #endif
 	} else if (p_rendering_driver == "opengl3") {
-#ifdef GLES3_ENABLED
+#if defined(GLES3_ENABLED) && !defined(MACOS_ENABLED)
 		graphics_extension = memnew(OpenXROpenGLExtension);
 		register_extension_wrapper(graphics_extension);
 #else