diff --git a/editor/plugins/script_editor_plugin.cpp b/editor/plugins/script_editor_plugin.cpp
index a584d357cd3..cf7c4789bd5 100644
--- a/editor/plugins/script_editor_plugin.cpp
+++ b/editor/plugins/script_editor_plugin.cpp
@@ -1561,6 +1561,30 @@ void ScriptEditor::_prepare_file_menu() {
 	menu->set_item_disabled(menu->get_item_index(FILE_RUN), current_is_doc);
 }
 
+void ScriptEditor::_file_menu_closed() {
+	PopupMenu *menu = file_menu->get_popup();
+
+	menu->set_item_disabled(menu->get_item_index(FILE_REOPEN_CLOSED), false);
+
+	menu->set_item_disabled(menu->get_item_index(FILE_SAVE), false);
+	menu->set_item_disabled(menu->get_item_index(FILE_SAVE_AS), false);
+	menu->set_item_disabled(menu->get_item_index(FILE_SAVE_ALL), false);
+
+	menu->set_item_disabled(menu->get_item_index(FILE_TOOL_RELOAD_SOFT), false);
+	menu->set_item_disabled(menu->get_item_index(FILE_COPY_PATH), false);
+	menu->set_item_disabled(menu->get_item_index(SHOW_IN_FILE_SYSTEM), false);
+
+	menu->set_item_disabled(menu->get_item_index(WINDOW_PREV), false);
+	menu->set_item_disabled(menu->get_item_index(WINDOW_NEXT), false);
+
+	menu->set_item_disabled(menu->get_item_index(FILE_CLOSE), false);
+	menu->set_item_disabled(menu->get_item_index(CLOSE_ALL), false);
+	menu->set_item_disabled(menu->get_item_index(CLOSE_OTHER_TABS), false);
+	menu->set_item_disabled(menu->get_item_index(CLOSE_DOCS), false);
+
+	menu->set_item_disabled(menu->get_item_index(FILE_RUN), false);
+}
+
 void ScriptEditor::_tab_changed(int p_which) {
 	ensure_select_current();
 }
@@ -3851,6 +3875,7 @@ ScriptEditor::ScriptEditor() {
 	file_menu->get_popup()->add_shortcut(ED_SHORTCUT("script_editor/toggle_scripts_panel", TTR("Toggle Scripts Panel"), KeyModifierMask::CMD_OR_CTRL | Key::BACKSLASH), TOGGLE_SCRIPTS_PANEL);
 	file_menu->get_popup()->connect("id_pressed", callable_mp(this, &ScriptEditor::_menu_option));
 	file_menu->get_popup()->connect("about_to_popup", callable_mp(this, &ScriptEditor::_prepare_file_menu));
+	file_menu->get_popup()->connect("popup_hide", callable_mp(this, &ScriptEditor::_file_menu_closed));
 
 	script_search_menu = memnew(MenuButton);
 	script_search_menu->set_text(TTR("Search"));
diff --git a/editor/plugins/script_editor_plugin.h b/editor/plugins/script_editor_plugin.h
index f8e684ae34c..7d2f5ad22a5 100644
--- a/editor/plugins/script_editor_plugin.h
+++ b/editor/plugins/script_editor_plugin.h
@@ -336,6 +336,7 @@ class ScriptEditor : public PanelContainer {
 	bool _has_docs_tab() const;
 	bool _has_script_tab() const;
 	void _prepare_file_menu();
+	void _file_menu_closed();
 
 	Tree *disk_changed_list = nullptr;
 	ConfirmationDialog *disk_changed = nullptr;